產品屬性:
產品名稱 | Aselacin C |
規格 | 100μg、500μg |
貨號 | EY-01Y19986 |
Cas No.: 156223-08-4
別名: N/A
化學名: N/A
分子式: C46H66N8O11
分子量: 907.1
溶解度:
儲存條件: -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Aselacin C is a cyclic pentapeptolide antagonist of endothelin receptor type A (ETA) and ETB originally isolated from Acremonium.1 It inhibits the binding of endothelin-1 to isolated bovine atrial membranes and porcine cerebral membranes, which endogenously express high levels of ETA and ETB, respectively, with IC50 values of 60 and 80 μg/ml, respectively.1.Jackson, M., Burres, N.S., Karwowski, J.P., et al.Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activityJ. Antibiot.47(5)523-527(1994)
特別提醒公司產品僅供科研使用