產品屬性：
產品名稱 | Silvestrol aglycone |
規(guī)格 | 10mM*1mL in DMSO、1mg、5mg、10mg |
貨號 | EY-01Y17565 |
Cas No.: 960365-65-5
別名: N/A
化學名: N/A
分子式: C27H26O8
分子量: 478.49
溶解度: DMSO: ≥ 106 mg/mL (221.53 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity[1].Silvestrol aglycone (Compound 4) inhibits the proliferation of MDA-MB-231 cells with an E50 of 20 ± 10 nM after 72 h[1].[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.
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