產(chǎn)品屬性：
產(chǎn)品名稱 | Zaurategrast ethyl ester |
規(guī)格 | 10mM*1mL in DMSO、5mg、10mg、25mg、50mg、100mg |
貨號 | EY-01Y14736 |
Cas No.: 455264-30-9
別名: N/A
化學(xué)名: N/A
分子式: C28H29BrN4O3
分子量: 549.46
溶解度: DMSO: 150 mg/mL (273.00 mM); H2O: < 0.1 mg/mL (insoluble)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2].α4β1/α4β7 integrin[1]Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91.
[2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76.
特別提醒公司產(chǎn)品僅供科研使用
