產(chǎn)品屬性：
產(chǎn)品名稱 | SI-2 hydrochloride |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y13503 |
Cas No.: N/A
別名: N/A
化學(xué)名: N/A
分子式: C15H15N5.HCl
分子量: 301.78
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent steroid receptor coactivator 3 (SRC-3) inhibitor. Reduces SRC1, SRC2 and SRC3 levels in breast cancer cell lines. Inhibits cell growth (IC50 = 3.4 nM), induces apoptosis and attenuates migration of MDA-MB48 breast cancer cells in vitro. Inhibits tumor growth in a MDA-MB48 cell breast cancer mouse model. Orally available.Song et al (2016) Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proc.Natl.Acad.Sci.U.S.A. 113 4970 PMID:27084884
特別提醒公司產(chǎn)品僅供科研使用
