產品屬性:
產品名稱 | β-Hydroxyisovalerylshikonin |
規格 | 1mg、5mg |
貨號 | EY-01Y12792 |
Cas No.: 7415-78-3
別名: N/A
化學名: N/A
分子式: C21H24O7
分子量: 388.41
溶解度: Soluble in DMSO
儲存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells[1].IC50: 0.7 μM (EGFR), 1 μM (v-Src)[1][1]. Hashimoto S, et al. Beta-hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases. Jpn J Cancer Res. 2002 Aug;93(8):944-51.
特別提醒公司產品僅供科研使用