產品屬性:
產品名稱 | p,p'-DDE |
規格 | 250mg、500mg |
貨號 | EY-01Y10996 |
Cas No.: 72-55-9
別名: N/A
化學名: N/A
分子式: C14H8Cl4
分子量: 318
溶解度: Chloroform: Slightly Soluble
儲存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
p,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). p,p'-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 8 μM. It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles. p,p'-DDE (50-100 μM) also decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro.
特別提醒公司產品僅供科研使用