產品屬性:
產品名稱 | γ-1-Melanocyte Stimulating Hormone (MSH), amide |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y12154 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C72H97N21O14S
分子量: 1512.9
溶解度: N/A
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake[1].[1]. Kathpalia PP, et al. The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone. Peptides. 2011 May;32(5):1068-72.
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